Antidepressant Clinical Trials Exclude Many People with Depression

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A provocative new study suggests that more than 80 percent of people with depression in the general population aren’t eligible for clinical trials of antidepressant drugs. Researchers comment that at least five patients would need to be screened to enroll just one patient meeting the typical inclusion and exclusion criteria for antidepressant registration trials (ARTs). Drs. Sheldon Preskorn and Matthew Macaluso of University of Kansas School of Medicine-Wichita and Dr. Madhukar Trivedi of Southwestern Medical School in Dallas led the study. The investigation illuminates some major differences between patients with depression

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Published By: Psych Central – Wednesday, 15 July, 2015

 

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